A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/132 (2006.01) A61K 31/133 (2006.01) A61K 31/135 (2006.01) A61K 31/198 (2006.01) A61K 31/395 (2006.01) A61P 27/02 (2006.01)
Patent
CA 2583110
This disclosure relates to methods of treating ocular diseases using polyamine analogs, particularly conformationally restricted polyamine analogs. The ocular diseases to be treated include a variety of ophthalmic disorders characterized by angiogenesis and/or neovascularization, including macular degeneration. Both wet macular degeneration and dry macular degeneration can be treated using the methods of the invention. The invention also provides ophthalmic formulations, including sustained release formulations and sustained release devices.
Cette invention porte sur des procédés de traitement de maladies oculaires avec des analogues de polyamine, en particulier des analogues de polyamine à conformation restreinte. Les maladies oculaires à traiter comprennent une variété de troubles ophtalmiques caractérisés par l'angiogenèse et/ou la néovascularisation, y compris la dégénérescence maculaire. Les formes mouillée et sèche de la dégénérescence maculaire peuvent être traitées à l'aide des procédés décrits dans cette invention. L'invention porte également sur des formulations ophtalmiques, y compris des formulations à libération prolongée et des dispositifs à libération prolongée.
Campochiaro Peter
Haidt Sterling
Marton Laurence J.
Borden Ladner Gervais Llp
Cellgate Inc.
The Johns Hopkins University
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