Stabilized and preserved ketotifen ophthalmic compositions

Details Stabilized and preserved ketotifen ophthalmic compositions Stabilized and preserved ketotifen ophthalmic compositions

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 31/4535 (2006.01)

Patent

CA 2619834

Ophthalmic compositions comprising ketotifen, a source of hydrogen peroxide providing an amount of hydrogen peroxide of from about 0.001 to about 0.1 % (w/v), one or more ocular-compatible hydrogen peroxide stabilizers, HPMC and CMC, and methods for the treatment and prevention of allergic conjunctivitis using these ophthalmic compositions are provided herein.

L'invention concerne des compositions ophtalmiques comprenant du kétotifène, une source de peroxyde d'hydrogène fournissant une quantité de peroxyde d'hydrogène comprise entre 0,001 et 0,1 % (M/V) approximativement, un ou plusieurs agents stabilisants à base de peroxyde d'hydrogène compatibles au niveau oculaire, de l'HPMC et de la CMC. L'invention concerne également des méthodes de traitement et de prévention de conjonctivite allergique au moyen de ces compositions.

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