Processes for production of optically active...

C - Chemistry – Metallurgy – 12 – P

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C12P 7/62 (2006.01)

Patent

CA 2113240

ABSTRACT A microorganism that is capable of acting a 4-halo-acetoacetic acid ester shown by the general formula: Image (I) wherein X represents a halogen atom and R repre- sents an optionally substituted alkyl group, alkenyl group, cycloalkyl group or aryl group, to produce an optically active 4-halo-3-hydroxybutyric acid ester or a preparation thereof is permitted to act on said 4- halo- acetoacetic acid ester and the product optically active 4-halo-3-hydroxybutyric acid ester is harvested. Thus, the desired optically active 4-halo-3- hydroxybutyric acid ester of high optical purity can be produced with commercial efficiency.

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