C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 311/19 (2006.01) A61K 31/18 (2006.01) A61K 31/445 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07C 311/29 (2006.01) C07C 311/44 (2006.01) C07D 207/48 (2006.01) C07D 211/96 (2006.01) C07D 213/53 (2006.01) C07D 215/36 (2006.01) C07D 223/06 (2006.01) C07D 277/06 (2006.01) C07D 277/80 (2006.01) C07D 309/06 (2006.01)
Patent
CA 2730708
The present invention provides a compound of formula (I) said compound is inhibitor of MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP- 12 and/ or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-12 and/or MMP-13. Finally, the present invention also provides pharmaceutical composition that include the compound of formula (I).
La présente invention concerne un composé de formule (I), ledit composé étant un inhibiteur de MMP-12 et/ou MMP-13, et peut donc être utilisé pour le traitement dun trouble ou dune maladie caractérisé par une activité anormale de MMP-12 et/ou MMP-13. En conséquence, le composé de formule (I) peut être utilisé dans le traitement de troubles ou de maladies médiés par MMP-12 et/ou MMP-13. Enfin, la présente invention concerne en outre une composition pharmaceutique qui comprend le composé de formule (I).
Mcquire Leslie Wighton
Rogel Olivier
Shultz Michael
Tommasi Ruben Alberto
Weiler Sven
Fetherstonhaugh & Co.
Novartis Ag
LandOfFree
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