C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 333/38 (2006.01) A61K 31/381 (2006.01) A61K 31/426 (2006.01) A61P 25/18 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01) C07D 277/56 (2006.01) C07D 333/34 (2006.01) C07D 409/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2621443
The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt or stereoisomer thereof. The compounds of the present invention are inhibitors of histone deacetylase (HDAC) and are useful for treating cellular proliferative diseases, including cancer. Further, the compounds of the present invention are useful for treating neurodegenerative diseases, schizophrenia and stroke among other diseases.
La présente invention concerne des composés de formule (I) ou un sel ou un stéréoisomère pharmaceutiquement acceptable de ceux-ci. Les composés de la présente invention sont des inhibiteurs de l'histone désacétylase (HDAC) et sont utiles pour traiter des maladies prolifératives cellulaires telles que le cancer. En outre, les composés de la présente invention sont utiles pour traiter des maladies neurodégénératives, la schizophrénie et l'accident cérébrovasculaire, entre autres maladies.
Ferrigno Federica
Jones Philip
Muraglia Ester
Ontoria Ontoria Jesus Maria
Scarpelli Rita
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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