C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12N 15/11 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2451919
Disclosed herein is a nucleic acid sequence that encodes a novel polypeptide. Also disclosed is a polypeptide encoded by the nucleic acid sequence , and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving this novel human nucleic acid and protein. The invention also provides nucleic acids containing single-nucleotide polymorphisms identified for transcribed human sequences, as well as methods of using the nucleic acids.
La présente invention concerne une séquence d'acides nucléiques codante pour un nouveau polypeptide. Cette invention concerne aussi un polypeptide codé par cette séquence d'acides nucléiques, des anticorps qui se lient de manière immunospécifique à ce polypeptide, ainsi que des dérivés, des variants, des mutants ou des fragments du polypeptide, du polynucléotide ou de l'anticorps susmentionnés. Cette invention concerne encore des techniques de thérapie, de diagnostic et de recherche destinées au diagnostic, au traitement et à la prévention de pathologies dans lesquelles ce nouvel acide nucléique et cette nouvelle protéine humaine interviennent. Cette invention concerne enfin des acides nucléiques contenant des polymorphismes nucléotidiques simples identifiés pour des séquences humaines transcrites, ainsi que des techniques d'utilisation de ces acides nucléiques.
Alsobrook John P. II
Bader Joel S.
Burgess Catherine E.
Grosse William M.
Curagen Corporation
Na
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