Binding peptides: methods for their generation and use

G - Physics – 01 – N

Patent

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G01N 33/543 (2006.01) C07K 1/22 (2006.01)

Patent

CA 2529001

Provided are means, methods for generating binding peptide associated with a suitable core region, the resulting proteinaceous molecule and uses thereof. The invention provides a solution to the problems associated with the use of binding molecules over their entire range of use. Binding molecules can be designed to accommodate extreme conditions of use such as extreme temperatures or pH. Alternatively, binding molecules can be designed to respond to very subtle changes in the environment.

L'invention porte sur des moyens, sur des procédés de génération d'un peptide de liaison associé à une région centrale appropriée, sur la molécule protéinique obtenue et sur ses utilisations. L'invention apporte une solution aux problèmes associés à l'utilisation de molécules de liaison sur leur plage complète d'utilisation. Les molécules de liaison peuvent être conçues pour s'adapter à des conditions extrêmes d'utilisation, telles que des températures extrêmes ou un pH extrême. En variante, les molécules de liaison peuvent être conçues pour répondre à des changements très subtils dans l'environnement.

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