Rapamycin conjugates and antibodies

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/18 (2006.01) A61K 31/435 (2006.01) C07H 19/01 (2006.01) C07K 16/12 (2006.01) G01N 33/53 (2006.01) G01N 33/533 (2006.01) G01N 33/577 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2161101

Provided are rapamycin conjugates which are useful as immunogenic molecules for the generation of antibodies specific for rapamycin or a derivative thereof, for measuring levels of rapamycin or derivatives thereof; for isolating rapamycin binding proteins; and detecting antibodies specific for rapamycin or derivatives thereof. This invention also provides monoclonal antibodies specific for rapamycin or a ring opened derivative of rapamycin.

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