Oligosaccharide aromatic glycoside sulfate

C - Chemistry – Metallurgy – 07 – H

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C07H 15/203 (2006.01) A61K 31/70 (2006.01) C08B 37/00 (2006.01)

Patent

CA 2077993

171 ABSTRACT OF THE DISCLOSURE A oligosaccharide aromatic glycoside sulfate or a physiologically acceptable salt of the same which is formed from same or different monosaccharides bonded by glycoside bonds, wherein the hydrogen atom in the hydroxyl group at the position-1 carbon atom at the terminal of the oligosaccharide is substituted with a group represented by Formula (I): - Y - (O)n - R (I) (in the formula, R represents an alkyl group having 1-18 carbon atoms, n is 0 or 1, O represents an oxygen atom, and Y represents an allylene group) and at least 10% of the remaining hydroxyl groups of the sugar subunits have been subjected to sulfated esterification; an anti-viral agent containing this oligosaccharide aromatic glycoside sulfate or physiologically acceptable salt of the same as an active component; and a oligosaccharide aromatic glycoside which functions as a production intermediate are disclosed. The anti-viral agent exhibits low toxicity and superior anti- viral activity, and is especially effective against viruses which are known to cause AIDS.

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