Fluorescent nanoparticles

Details Fluorescent nanoparticles Fluorescent nanoparticles

A - Human Necessities

61

K

A61K 49/00 (2006.01) C09K 11/06 (2006.01) C09K 11/74 (2006.01) C09K 11/88 (2006.01)

Patent

CA 2628678

Disclosed is the use of fluorescent nanoparticles containing an inorganic core, a passivation layer, and specific ligands, the inorganic core with the passivation layer having a maximum hydrodynamic diameter of 15 nm, preferably 10 nm, most preferably 5 nm, for producing an in vivo diagnostic agent. The inventive nanoparticles are provided with an emission of less than 700 nm.

L'invention concerne l'utilisation de nanoparticules fluorescentes contenant un noyau anorganique, une couche de passivation et des ligands spécifiques, le diamètre hydrodynamique du noyau anorganique revêtu de la couche de passivation n'excédant pas 15 nm, de préférence 10 nm, notamment 5 nm, pour la fabrication d'un agent diagnostique in vivo. Les nanoparticules selon l'invention présentent une émission inférieure à 700 nm.

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