C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 19/00 (2006.01) A61K 39/00 (2006.01) A61K 39/295 (2006.01) A61K 39/385 (2006.01) C07K 14/16 (2006.01) C07K 14/35 (2006.01) C12N 15/62 (2006.01)
Patent
CA 2164298
The present invention relates to stress proteins and methods of modulating an individual's immune response. In particular, it relates to the use of such stress proteins in immune therapy and prophylaxis, which results in an induction or enhancement of an individual's immune response and as an immunotherapeutic agent which results in a decrease of an individual's immune response to his or her own cells. The present invention also relates to compositions comprising a stress protein joined to another component, such as a fusion protein in which a stress protein is fused to an antigen.
L'invention concerne des protéines du stress et des procédés de modulation de la réponse immunitaire d'un individu. L'invention porte, plus particulièrement, sur l'utilisation desdites protéines du stress dans la thérapie et la prophylaxie génique de manière à induire ou augmenter la réponse immunitatire d'un individu, et en tant qu'agent immunothérapeutique de manière à réduire la réponse immunitaire d'un individu contre ses propres cellules. Elle se rapporte également à des compositions contenant une protéine du stress liée à un autre composant tel qu'une protéine de fusion dans laquelle la protéine du stress est soudée à un antigène.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Whitehead Institute For Biomedical Research
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