A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61P 13/12 (2006.01)
Patent
CA 2585056
The present invention relates generally to methods of for the prevention and treatment for renal disease. In particular, the invention relates to methods of prevention and treatment of mammals, including humans, which are at risk of developing renal failure. This is generally in the field of treatment or prevention of acute renal failure by administration of the anti-apoptotic molecule survivin. The invention also includes the treatment of kidney transplants (renal allografts) to prolong survival of the graft during cold ischemia and immediately after transplantation.
La présente invention décrit, de manière générale, des méthodes de prévention et de traitement de maladies rénales. La présente invention décrit en particulier des méthodes de prévention et de traitement de mammifères, humains compris, qui risquent de développer une insuffisance rénale. La présente invention se rapporte plus particulièrement au domaine du traitement prophylactique ou thérapeutique d~insuffisances rénales aiguës, par administration de survivine, une molécule anti-apoptotique. La présente invention a également pour objet le traitement d'allogreffes rénales visant à retarder le rejet de la greffe en cas d~ischémie froide, et immédiatement après transplantation.
D. Collen Research Foundation Vzw
Fetherstonhaugh & Co.
Vib Vzw
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