Medical adhesives

A - Human Necessities – 61 – M

Patent

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Details

A61M 29/02 (2006.01) A61F 2/06 (2006.01) A61K 47/48 (2006.01) A61K 51/12 (2006.01) A61L 15/44 (2006.01) A61L 27/54 (2006.01) A61L 29/16 (2006.01) A61L 31/16 (2006.01) A61F 2/00 (2006.01) A61N 5/10 (2006.01)

Patent

CA 2395672

Medical devices include biocompatible materials (102) and a plurality of exogenous storage structures (100). The exogenous storage structures (100) store a therapeutic agent (104) which acts to inhibit restenosis. In some embodiments, the therapeutic agents are radioactive metal ions. In other embodiments, the medical device has an expandable structure with particles of therapeutic agent (104) on its surface. The particles of therapeutic agent (104) are delivered into a region susceptible to restenosis by direct application of the medical device against the adjacent wall.

L'invention concerne des dispositifs médicaux comprend des matériaux biocompatibles (102) et une pluralité de structures de stockage exogènes (100). Ces structures (100) stockent un agent thérapeutique (104) inhibant la resténose. Dans quelques modes de réalisation, les agents thérapeutiques sont des ions métalliques radioactifs. Dans d'autres modes de réalisation, le dispositif médical présente une structure extensible présentant des particules d'agent thérapeutique (104) sur sa surface. Les particules d'agent thérapeutique (104) sont distribuées dans une région présentant des risques de resténose par application directe du dispositif médical contre la paroi adjacente.

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