Diaryl-2-(5h)-furanones as cox-2 inhibitors

Details Diaryl-2-(5h)-furanones as cox-2 inhibitors Diaryl-2-(5h)-furanones as cox-2 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 307/58 (2006.01) A61K 31/12 (2006.01) A61K 31/18 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) A61K 31/66 (2006.01) C07C 317/24 (2006.01) C07D 307/79 (2006.01) C07D 307/83 (2006.01) C07D 307/94 (2006.01) C07D 333/32 (2006.01) C07D 333/78 (2006.01) C07D 405/02 (2006.01) C07D 405/04 (2006.01) C07D 407/04 (2006.01) C07D 409/04 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01) C07D 491/10 (2006.01) C07D 491/107 (2006.01) C07D 493/10 (2006.01) C07D 495/10 (2006.01) C07F 9/53 (2006.01) C07F 9/655

Patent

CA 2206978

The invention encompasses the novel compound of Formula (I) as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula (I). The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula (I).

La présente invention a pour objet le nouveau composé de la formule (I) ainsi qu'un procédé de traitement des maladies induites par la cyclooxygénase-2. Ce procédé consiste à administrer à un patient une dose thérapeutiquement efficace non toxique d'un composé de la formule (I). L'invention traite également de certaines compositions pharmaceutiques pour traiter les maladies induites par la cyclooxygénase-2 comprenant des composés de la formule (I).

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