Preparations comprising a fluorocarbon and a...

A - Human Necessities – 61 – K

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A61K 9/107 (2006.01) A61K 9/00 (2006.01) B01F 17/00 (2006.01) A61K 7/00 (1990.01)

Patent

CA 2113542

2113542 9301798 PCTABS00019 Fluorocarbon emulsions comprising a stabilizing, particle size controlling fluorophilic/hydrophilic compound which can have the formula RF1-W-RH1 (I), wherein RF1 is a linear, branched or cyclic C2-14 fluorocarbon group; RH1 is a linear, branched or cyclic C2-18 saturated or unsaturated hydrocarbon group; and W is absent or is a bivalent species chosen from the group consisting of -O-, -S-, or various fluorinated structures. Use of the fluorophilic/lipophilic compound in the dispersions of the invention provides stable particle size and efficient emulsification. The dispersions of the invention can comprise biologically useful additive and can be used for various purposes, as oxygen carriers, contrast agents, or diagnostic agents.

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