C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/00 (2006.01) A61K 31/7088 (2006.01) A61K 31/7105 (2006.01) A61K 48/00 (2006.01) A61P 25/08 (2006.01) A61P 35/00 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2505842
The present invention provides isolated antisense molecules targeted to BC200 RNA. The subject antisense molecules are useful in treating various neurological disorders and carcinomas in a subject. Also provided are methods of treating a neurological disorder or cancer in a subject by administering a therapeutically effective amount of a subject antisense molecule. A method for treating epilepsy in a patient by administering an effective amount of BC200 RNA is also provided. Further, kits comprising a subject antisense molecule and a pharmaceutically acceptable carrier are provided by the present invention.
La présente invention concerne les molécules antisens isolées ciblées sur l'ARN BC200. Ces molécules antisens sont utiles dans le traitement de divers troubles neurologiques et de carcinomes chez un sujet. Elle concerne aussi des méthodes de traitement d'un trouble neurologique ou d'un cancer chez un sujet consistant à administrer une quantité thérapeutiquement efficace d'une molécule antisens. Elle concerne encore une méthode de traitement de l'épilepsie chez un patient en lui administrant une quantité efficace d'ARN BC200. Elle concerne enfin des kits comportant une molécule antisens et un support acceptable sur le plan pharmaceutique.
Mcfadden Fincham
The Research Foundation Of State University Of New York
LandOfFree
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