Compositions and methods of use for a fibroblast growth factor

Details Compositions and methods of use for a fibroblast growth factor Compositions and methods of use for a fibroblast growth factor

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A61K 38/18 (2006.01) A61P 1/00 (2006.01) A61P 17/02 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) C07K 14/50 (2006.01) C12N 15/63 (2006.01) C12N 15/79 (2006.01) C12P 21/02 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2548538

The present invention generally relates to compositions and methods of use for a fibroblast growth factor ("FGF"). More particularly, the present invention relates to a nucleotide polymorphism (SNP) of FGF-20, and its fragments, derivatives, variants, homologs, and analogs, as well as their uses in wound healing, and prevention and/or treatment of certain diseases, including but are not limited to, stroke, radiation sickness, mucositis, inflammatory bowel disease, and inflammation (osteoarthritis and rheumatoid arthritis).

De façon générale, La présente invention concerne des compositions et des méthodes utiles pour facteur de croissance des fibroblastes ("FGF"). Plus particulièrement, l'invention concerne un polymorphisme de nucléotides (SNP) de FGF-20, et ses fragments, dérivés, variantes, homologues et analogues, ainsi que leurs utilisations pour la cicatrisation des blessures, la prévention et/ou le traitement de certaines maladies, dont, notamment, les attaques, la maladie des rayons, la mucosite, la maladie intestinale inflammatoire et les inflammations (ostéoarthrose et polyarthrite rhumatoïde).

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