Modulation

Details Modulation Modulation

A - Human Necessities

61

K

A61K 38/16 (2006.01) A61K 31/00 (2006.01) A61K 45/06 (2006.01) A61K 48/00 (2006.01) A61K 49/00 (2006.01) A61P 25/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2397005

A method of treatment is described. The method comprises administering to a subject in need of same an agent, wherein said agent is capable of causing a dopaminergic neuron to enter bursting mode and/or of preventing it from leaving bursting mode. In a preferred aspect, the said agent modulates: a T-type channel and/or an SK (preferably SK3) channel and/or the coupling of a T-type channel with an SK (preferably SK3) channel.

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