Method for selectively modulating the interactions between...

Details Method for selectively modulating the interactions between... Method for selectively modulating the interactions between...

G - Physics

01

N

G01N 33/68 (2006.01) C07K 14/47 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2323514

The present invention, based on the discovery of a new biological phenomena, provides methods and compositions for use in identifying agents which modulate the interaction between Survivin and polymerized tubulin or the mitotic spindles. Related methods and compositions can be used to modulate the interactions between Survivin and polymerized tubulin or the mitotic spindles, thereby modulating Survivin regulated apoptosis.

La présente invention, fondée sur la découverte d'un nouveau phénomène biologique, concerne des méthodes et des compositions destinées à être utilisées pour identifier des agents modulant l'interaction entre Survivine et la tubuline polymérisée ou les faisceaux mitotiques. Des méthodes et des compositions associées peuvent être utilisées pour moduler les interactions entre Survivine et la tubuline polymérisée ou les faisceaux mitotiques, ce qui permet de moduler l'apoptose régulée par Survivine.

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