Treatment of age-related macular degeneration using...

A - Human Necessities – 61 – K

Patent

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A61K 31/381 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2680833

The present invention provides methods for identifying a patient at risk for developing AMD by identifying the presence of the Y402H polymorphism or other at risk variants in the complement factor H gene. The present invention further provides methods for treating persons having AMD or at risk for developing AMD as a result of having the Y402H polymorphism or other at risk variants in the complement factor H gene.

La présente invention concerne des procédés d'identification d'un patient risquant de développer l'AMD en identifiant la présence du polymorphisme Y402H ou autres à des variantes de risque dans le gène du facteur H du complément. La présente invention propose en outre des procédés de traitement de personnes ayant l'AMD ou risquant de développer l'AMD après avoir eu le polymorphisme Y402H ou autres à des variantes de risque dans le gène du facteur H du complément.

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