G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/68 (2006.01) C12Q 1/48 (2006.01)
Patent
CA 2513470
Modulation of Deubiquitinase Family Members The present invention relates to the therapeutic treatment of conditions by modulating members of the deubiquitinase family, and also to assays for identifying substances which may be useful in such treatments, as well as to the treatment of cylindromatosis and more generally to the modulation of other conditions associated with activation of the transcription factor NF-KB, such as inflammation.
L'invention concerne le traitement thérapeutique de maladies au moyen de membres modulateurs de la famille de la deubiquitinase, des essais permettant d'identifier des substances pouvant être utiles dans ces traitements, le traitement de la cylindromatose et, d'une manière plus générale, la modulation d'autres maladies associées à l'activation du facteur de transcription NF-B, telles que l'inflammation.?¿
Bernards Rene
Brummelkamp Thijn R.
Dirac Annette M.
Nijman Sebastian M.
Smart & Biggar
Topotarget Uk Limited
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