Process for preparing alkoxypyrazine derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 241/18 (2006.01) C07D 241/20 (2006.01) C07D 241/24 (2006.01)

Patent

CA 2241933

A novel process for preparing alkoxypyrazine derivatives of the general formula: Image in which R1 denotes hydrogen, alkyl or aryl, R2 denotes hydrogen, alkyl, -CONH2, -COOR4 or -C (NH) OR4, in which R4 is alkyl, and R3 denotes alkyl or aryl, is described. The process involves reacting a glyoxal derivative of the general formula: Image and an aminoimidate of the general formula Image The alkoxypyrazine derivatives are important intermediates for preparing pharmaceutically active compounds.

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