Piperazine derivatives, medicaments comprising these...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 211/56 (2006.01) A61K 31/495 (2006.01) A61K 31/55 (2006.01) C07D 207/14 (2006.01) C07D 211/34 (2006.01) C07D 211/58 (2006.01) C07D 223/12 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/00 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2207618

Piperazine derivatives have the general formula (I), in which Ra, Y1 to Y3 and E have the definitions given in the first claim. Also disclosed are their tautomers, their stereoisomers, including their mixtures and their salts, in particular their physiologically tolerable salts with inorganic or organic acids or bases, having valuable pharmacological properties, preferably aggregation-inhibiting effects, medicaments containing these compounds, their use and a process for preparing the same.

L'invention concerne des dérivés de pipérazine répondant à la formule générale (I), dans laquelle R¿a?, Y¿1? à Y¿3? et E ont la définition donnée dans la première revendication, leurs tautomères, leurs stéréoisomères, y compris leurs mélanges et leurs sels, notamment leurs sels physiologiquement tolérables avec des acides ou des bases inorganiques ou organiques, qui présentent de précieuses propriétés pharmacologiques, de préférence un effet inhibiteur de l'agrégation, des médicaments contenant ces composés, leur utilisation et leur procédé de préparation.

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