Methods for producing 5'-nucleic acid-protein conjugates

Details Methods for producing 5'-nucleic acid-protein conjugates Methods for producing 5'-nucleic acid-protein conjugates

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) A61K 38/03 (2006.01) A61K 38/16 (2006.01) C07K 14/00 (2006.01) C07K 17/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2373047

Disclosed herein is a method for generating a 5'-nucleic acid-protein conjugate, the method involving: (a) providing a nucleic acid which carries a reactive group at its 5'end; (b) providing a non-derivatized protein; and (c) contacting the nucleic acid and the protein under conditions which allow the reactive group to react with the N-terminus of the protein, thereby forming a 5'-nucleic acid-protein conjugate. Also disclosed herein are 5'-nucleic acid- protein conjugates and methods for their use.

L'invention a pour objet un procédé pour générer un conjugat de 5'-acide nucléique-protéine. Ce procédé consiste à (a) fournir un acide nucléique qui supporte un groupe réactif au niveau de son extrémité 5'; (b) fournir une protéine non dérivée, et (c) mettre en contact l'acide nucléique et la protéine dans des conditions qui permettent au groupe réactif de réagir avec la terminaison N de la protéine pour former ainsi un conjugat 5'-acide nucléique-protéine. L'invention traite également de conjugats de 5'-acide nucléique-protéine, et de procédés d'utilisation de ces derniers.

Affiliated with

Also associated with

Rating

Methods for producing 5'-nucleic acid-protein conjugates does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods for producing 5'-nucleic acid-protein conjugates, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for producing 5'-nucleic acid-protein conjugates will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1683965