Tetrahydroisoquinolyl acetamide derivatives for use as...

Details Tetrahydroisoquinolyl acetamide derivatives for use as... Tetrahydroisoquinolyl acetamide derivatives for use as...

C - Chemistry, Metallurgy

07

D

C07D 217/02 (2006.01) A61K 31/472 (2006.01) A61P 3/04 (2006.01) A61P 25/20 (2006.01) C07D 217/04 (2006.01) C07D 217/16 (2006.01) C07D 217/18 (2006.01) C07D 217/20 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2518945

The invention relates to novel acetamide derivatives of formula (I) and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of such compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.

Cette invention se rapporte à de nouveaux dérivés d'acétamide représentés par la formule (I) et à leur utilisation comme principes actifs dans la préparation de compositions pharmaceutiques. Cette invention concerne également des aspects connexes tels que des procédés de préparation de ces composés, des compositions pharmaceutiques contenant un ou plusieurs de ces composés et, en particulier, leur utilisation comme antagonistes des récepteurs d'orexine.

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