Substituted enaminones, their derivatives and uses thereof

Details Substituted enaminones, their derivatives and uses thereof Substituted enaminones, their derivatives and uses thereof

C - Chemistry, Metallurgy

07

C

C07C 211/00 (2006.01)

Patent

CA 2565627

The invention relates to substituted enaminones of Formula (I) and their derivatives and the discovery that these compounds modulate the effect of .gamma.-aminobutyric acid (GABA) on the GABAA receptor complex in a therapeutically relevant fashion and may be used to ameliorate CNS disorders amenable to modulation of the GABAA receptor complex. Formula: (I).

L'invention concerne des énaminones substitués correspondant à la formule (I) et leurs dérivés, ainsi que la découverte selon laquelle ces composés modulent l'effet de l'acide ?-aminobutyrique (GABA) sur le complexe de récepteurs GABA<SB>A</SB> d'une façon acceptable de point de vue thérapeutique, et peuvent s'utiliser pour traiter des troubles du système nerveux central qui peuvent être traités par la modulation du complexe de récepteurs GABA<SB>A</SB>. Formule: (I).

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