Method and composition for the treatment of thrombosis in a...

Details Method and composition for the treatment of thrombosis in a... Method and composition for the treatment of thrombosis in a...

A - Human Necessities

61

K

167/103.33

A61K 38/49 (2006.01) A61K 9/127 (2006.01) A61K 9/50 (2006.01) A61K 38/16 (2006.01)

Patent

CA 2016949

A composition comprising a plurality of microcapsules suitable for parenteral injection into a mammal comprising a streptokinase-containing core, and a semi- permeable biocompatible layer surrounding the core permitting controlled release of at least a portion of the streptokinase. A method of reducing the time required for reperfusion of an artery containing a thrombus and a method to reduce the standard dosage requirement of a plasminogen activator in a mammal comprising intravenous injection of a composition comprising a plurality of microcapsules comprising a plasminogen activator core surrounded by a controlled release semi-permeable layer.

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