Ion channel assay methods

Details Ion channel assay methods Ion channel assay methods

C - Chemistry, Metallurgy

12

Q

C12Q 1/02 (2006.01)

Patent

CA 2532973

A method of characterizing the biological activity of a candidate compound may include exposing cells to the candidate compound, and then exposing the cells to a repetitive application of electric fields so as to set the transmembrane potential to a level corresponding to a pre-selected voltage dependent state of a target ion channel.

Une méthode de caractérisation de l'activité biologique d'un composé candidat peut consister à exposer des cellules aux composé candidat puis à exposer les cellules à une application répétée de champs électriques de manière à fixer le potentiel transmembranaire à un niveau correspondant à une tension présélectionnée dépendant de l'état d'un canal ionique cible.

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