Blood extraction flow control calibration system and method

A - Human Necessities – 61 – M

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Details

A61M 1/36 (2006.01) G05D 7/00 (2006.01) G05D 7/06 (2006.01) A61M 1/30 (2006.01)

Patent

CA 2136419

A method and system for calibrating and controlling the with- drawal of a fluid, such as blood, from a fluid source, such as a blood vessel, includes a fluid pump (26), a pressure sensor (24), a flow rate sensor, and a microprocessor based flow control subsystem. The flow control subsystem optimizes the flow rate by sensing zero flow rate pressure within the subject, making a plurality of periodic flow path pressure measurements and extrapolating a calibration flow rate curve (I10). A control curve (130) is generated by utilizing the zero- flow rate pressure point ( 100), the slope of the calibration curve ( 110), and an empirically predetermined pressure offset value (150). The blood pump (26) is then operated at a maximum speed that is limited by the flow control curve ( 130) to maximize flow without occlusion or collapse of the blood vessel during blood withdrawal. The method and system of the invention is particularly applicable to automated apheresis system.

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