Process for the preparation of 3-keto, 5-hydroxy simvastatin...

Details Process for the preparation of 3-keto, 5-hydroxy simvastatin... Process for the preparation of 3-keto, 5-hydroxy simvastatin...

C - Chemistry, Metallurgy

12

P

C12P 17/06 (2006.01) C07C 69/738 (2006.01) C07D 309/30 (2006.01)

Patent

CA 2019480

14/MW12 17845 TITLE OF THE INVENTION PROCESS FOR THE PREPARATION OF 3-KETO, 5-HYDROXY SIMVASTATIN ANALOGS ABSTRACT OF THE INVENTION A biotransformation for the formation of a 3-keto-5-hydroxy simvastation analog (I) or a 8- acyloxy derivative thereof is disclosed. Image (I)

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