Combinations of indacaterol derivatives and other agents for...

A - Human Necessities – 61 – K

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A61K 31/4704 (2006.01) A61K 45/06 (2006.01) A61P 11/06 (2006.01)

Patent

CA 2608704

A medicament comprising, separately or together, (A) a compound of formula (I) in free or salt or solvate form, where W, Rx, Ry, R1, R2, R3, R4, R5, R6 and R7 have the meanings as indicated in the specification, and (B) one or more of compounds selected from the group consisting of A2A agonists, A2B antagonists, antihistamines, caspase inhibitors, ENaC inhibitors, LTB4 antagonists, LTD4 antagonists and serine protease inhibitors, for simultaneous, sequential or separate administration in the treatment of an inflammatory or obstructive airways disease.

L'invention concerne un médicament comprenant, séparément ou ensemble, (A) un composé de formule (I), se présentant sous une forme libre, ou sous une forme de sels ou de solvates, dans cette formule, W, Rx, Ry, R1, R2, R3, R4, R5, R6 et R7 présentent les significations indiquées dans la description, et (B) au moins un composé sélectionné dans le groupe comprenant: des agonistes de A2A, des antagonistes de A2B, des antihistamines, des inhibiteurs de caspase, des inhibiteurs de ENaC, des antagonistes de LTB4, des antagonistes de LTD4 et des inhibiteurs de sérine protéase, pour une administration simultanée, séquentielle ou séparée, dans un traitement de maladies inflammatoires ou obstructives des voies respiratoires.

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