C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2728736
Methods and compositions for diagnosis and/or analysis of a condition in a mammal are disclosed in which RNA from microvesicles is enriched and differentiated to so obtain a result that is indicative of the condition of tissue or organ from which the microvesicle originated. In especially preferred embodiments, the condition is a neoplastic disease of a human and can be identified and staged by differential analysis of one or more distinct RNAs, optionally together with identification and analysis of a non-RNA component of the microvesicle.
La présente invention concerne des procédés et des compositions pour le diagnostic et/ou lanalyse dune pathologie chez un mammifère dans lesquels de lARN de microvésicules est enrichi et différencié de manière à obtenir un résultat qui est indicatif de la pathologie du tissu ou de lorgane duquel les microvésicules proviennent. Dans des modes de réalisation particulièrement préférés, la pathologie est une maladie néoplasique dun humain et peut être identifiée et stadifiée par analyse différentielle dun ou plusieurs ARN distincts, éventuellement avec lidentification et lanalyse dun composant non-ARN de la microvésicule.
Gowling Lafleur Henderson Llp
Proxy Life Science Holdings Inc.
LandOfFree
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