Use of oxcarbazepine for the treatment of diabetic...

A - Human Necessities – 61 – K

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Details

A61K 31/55 (2006.01) A61P 25/20 (2006.01) A61P 29/02 (2006.01)

Patent

CA 2537060

The present invention provides for novel uses of the carbamazepine derivative of formula (I) and its pharmaceutically acceptable salts, in particular an improved regimen for the administration of the carbamazepine derivative of formula (I) and the pharmaceutically acceptable salts thereof for the treatment of patients suffering from pain, in particular neuropathic pain, especially diabetic neuropathic pain, and the improvement of sleep; the use of oxcarbazepine for the manufacture of a pharmaceutical composition for the treatment of pain or the manufacture of a pharmaceutical composition for the improvement of sleep in human patients suffering from chronic pain; pharmaceutical compositions comprising oxcarbazepine as sole active ingredient for the treatment of pain or for the improvement of sleep in human patients suffering from chronic pain and to packages comprising a pharmaceutical composition comprising as sole active ingredient oxcarbazepine together with instructions for the treatment of pain or together with instructions for improvement of sleep in human patients suffering from chronic pain.

L'invention concerne de nouvelles utilisations d'un dérivé de carbamazépine de formule (I) et de ses sels pharmaceutiquement acceptables. L'invention concerne en particulier un régime amélioré d'administration dudit dérivé de carbamazépine de formule (I) et desdits sels pharmaceutiquement acceptables dans le traitement de patients souffrant de douleurs, notamment de douleurs liées à la neuropathie, en particulier à la neuropathie diabétique, et dans l'amélioration du sommeil. L'invention concerne également l'utilisation d'oxcarbazépine dans la fabrication d'une composition pharmaceutique destinée à traiter la douleur ou d'une composition pharmaceutique destinée à améliorer le sommeil de patients souffrant de douleurs chroniques. L'invention concerne encore des compositions pharmaceutiques contenant de l'oxcarbazépine comme seul principe actif, destinées à traiter la douleur ou à améliorer le sommeil de patients souffrant de douleurs chroniques. L'invention concerne enfin des emballages contenant une composition pharmaceutique ayant pour seul principe actif de l'oxcarbazépine, ainsi que des instructions relatives au traitement de la douleur ou à l'amélioration du sommeil de patients souffrant de douleurs chroniques.

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