Method for producing a mixture of bacteriophages and the use...

A - Human Necessities – 61 – K

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A61K 35/76 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2717534

The invention relates to a method for producing a mixture of bacteriophages, wherein at least two different bacte-riophage strains have been increased separately, wherein a staphylococcus strain having one strain each of a bacteriophage that can lyse staphylococci is grown in a preculture, and then further reproduced in a main culture, and then purified, and the various strains are then mixed, wherein the mixture of bacteriophages used comprises at least two different serotypes of bacteriophages that lyse the specific bacteria of the species staphylococcus.

L'invention concerne un procédé de préparation d'un mélange de bactériophages, dans lequel au moins deux souches distinctes de bactériophages sont multipliées séparément, une souche de staphylocoques étant, dans une préculture, cultivée avec chaque souche d'un bactériophage à même de lyser des staphylocoques, pour subir une multiplication plus poussée dans une culture principale, cette couche étant ensuite purifiée, et les différentes souches étant ensuite mélangées, le mélange utilisé de bactériophages contenant deux sérotypes différents de bactériophages qui lysent d'une manière spécifique des bactéries de l'espèce Staphylococcus.

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