Fibrate-statin combinations with reduced fed-fasted effects

Details Fibrate-statin combinations with reduced fed-fasted effects Fibrate-statin combinations with reduced fed-fasted effects

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 31/216 (2006.01) A61K 31/22 (2006.01) A61K 31/365 (2006.01) A61K 31/366 (2006.01) A61K 31/40 (2006.01) A61K 31/405 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) A61K 31/66 (2006.01) A61K 45/06 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2440355

This invention discloses an orally administered pharmaceutical composition for the treatment of elevated levels of cholesterol and related conditions comprising a statin and fenofibrate in the form of microparticles of solid fenofibrate that are stabilized by phospholipid as a surface active substance, wherein a therapeutically effective amount of the composition provides the statin and a quantity of fenofibrate to a fasted human patient that is greater than 80 % of the quantity of fenofibrate provided by the same amount of the composition when administered to the same patient who has been fed a high fat meal.

L'invention concerne une composition pharmaceutique administrée par voie orale, destinée à traiter des niveaux élevés de cholestérol et des états pathologiques associés, comprenant une statine et un fénofibrate sous la forme de microparticules de fénofibrate solide qui sont stabilisées par un phospholipide utilisé en tant qu'agent de surface, une dose efficace sur le plan thérapeutique de la composition fournit de la statine et une quantité de fénofibrate à un patient humain à jeun, qui est supérieure à 80 % de la quantité de fénofibrate fournie par la même quantité de composition, lors de son administration au même patient ayant mangé un repas riche en graisses.

Affiliated with

Also associated with

Rating

Fibrate-statin combinations with reduced fed-fasted effects does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fibrate-statin combinations with reduced fed-fasted effects, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fibrate-statin combinations with reduced fed-fasted effects will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1686954