Use of thiazolidinediones for the treatment of...

A - Human Necessities – 61 – K

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A61K 31/505 (2006.01) A61K 31/42 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2161116

The use of a compound of formula (I) or a tautomeric form thereof and/or a phar- maceutically acceptable salt thereof and/or a pharmaceutically acceptable solvate thereof, wherein: A1 represents a substituted or unsub- stituted aromatic hetercyclyl group; R1 rep- resents a hydrogen atom, an alkyl group, an acyl group, an arakyl group, wherein the aryl moiety may be substituted or unsubstituted, or a substituted or unsubstituted aryl group; R2 and R3 each represent hydrogen, or R2 and R3 together represent a bond; A2 represents a benzene ring having in total up to five substituents; and n represents an integer in the range of from 2 to 6, for the manufacture of a medicament for use in the treatment and/or prophylaxis atherosclerosis and/or for the regulation of appetite and food intake.

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