Compositions and methods relating to dna mismatch repair genes

Details Compositions and methods relating to dna mismatch repair genes Compositions and methods relating to dna mismatch repair genes

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2179285

Genomic sequences of human mismatch repair genes are described, as are methods of detecting mutations and/or polymorphisms in those genes. Also described are methods of diagnosing cancer susceptibility in a subject, and methods of identifying and classifying mismatch-repair-defective tumors. In particular, sequences and methods relating to human mutL homologs, hMLHI and hPMSI gene are provided.

L'invention décrit des séquences génomiques de gènes de réparation de mésappariements de l'ADN, ainsi que des procédés de détection des mutations et/ou des polymorphismes de ces gènes. Elle décrit également des procédés de diagnostic de la sensibilité au cancer d'un sujet, et des procédés d'identification et de classification des tumeurs présentant des défauts de réparation des mésappariements. Elle prévoit, en particulier, des séquences et des procédés concernant les homologues mutL humains, les gènes hMLH1 et hPMS1.

Affiliated with

Also associated with

Rating

Compositions and methods relating to dna mismatch repair genes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions and methods relating to dna mismatch repair genes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods relating to dna mismatch repair genes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1687482