Posaconazole polymer conjugates and methods of treatment...

Details Posaconazole polymer conjugates and methods of treatment... Posaconazole polymer conjugates and methods of treatment...

C - Chemistry, Metallurgy

08

G

C08G 65/333 (2006.01) A61K 47/48 (2006.01) A61P 31/10 (2006.01) A61P 35/00 (2006.01) A61K 31/496 (2006.01)

Patent

CA 2675411

Improved posaconazole-based compositions and methods of treating and preventing fungal infections, cancer or metastatic diseases are disclosed. In preferred aspects, the conjugates are PEG-posaconazole conjugates in which the PEG has a molecular weight of about 20,000 daltons.

L'invention concerne des compositions à base de posaconazole ainsi que des méthodes de traitement et de prévention des infections fongiques, du cancer ou des maladies métastatiques. Selon des aspects préférés, les conjugués sont des conjugués PEG-posaconazole dans lesquels le PEG présente un poids moléculaire d'environ 20.000 daltons.

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