Apparatus and method for the delivery of drugs and genes...

A - Human Necessities – 61 – N

Patent

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A61N 1/30 (2006.01) A61N 1/32 (2006.01)

Patent

CA 2340075

An electrode assembly for an apparatus for and a method of trans-surface molecular delivery, including a non-conductive carrier having a proximal surface, a distal surface, and a plurality of through holes from the proximal surface to the distal surface, a first electrode disposed on at least a portion of the distal surface and extending through at least a portion of the plurality of through holes and onto at least a portion of the proximal surface, a second electrode disposed on at least a portion of the proximal surface and in closely spaced relation with the first electrode for engaging a tissue surface through which to apply an electric field, and an insulating barrier that is disposed on at least a portion of the proximal surface of the carrier between the first electrode and the second electrode.

L'invention porte sur un ensemble électrode destiné à un appareil d'administration de molécules par une surface et sur le procédé correspondant. Cet appareil comprend un support non conducteur comportant une surface proximale, une surface distale et une pluralité de trous traversants s'étendant de la surface proximale à la surface distale; une première électrode placée sur au moins une partie de la surface distale et s'étendant dans au moins une partie de la pluralité de trous traversants et sur au moins une partie de la surface proximale, une seconde électrode placée sur au moins une partie de la surface proximale et rapprochée de la première électrode de façon à venir en contact avec une surface du tissu dans laquelle on applique un champ électrique, et une barrière isolante placée sur au moins une partie de la surface proximale du support entre la première et la seconde électrode.

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