Hvc binding protein

Details Hvc binding protein Hvc binding protein

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) C07K 1/14 (2006.01) C12N 15/85 (2006.01) G01N 33/566 (2006.01) G01N 33/576 (2006.01)

Patent

CA 2227301

A functionally unglycosylated transmembrane protein having a molecular weight of about 24kd which is ubiquitous in human cells and exhibits the same species specificity as hepatitis C virus. The protein is capable of binding to HCV surface proteins and is a putative HCV cellular receptor. As such it has many applications in the fields of diagnosis and treatment of HCV infection and in the design of HCV therapeutics.

Protéine membranaire à fonction non glycosylée possédant un poids moléculaire d'environ 24kd, ce qui est répandu dans les cellules humaines et présente la même spécificité d'espèce que le virus de l'hépatite C. Cette protéine est capable de se lier aux protéines de surface de HCV et est un récepteur cellulaire supposé de HCV. Ses mises en application sont nombreuses dans les domaines du diagnostic et du traitement de l'infection par HCV, ainsi que de la préparation de produits thérapeutiques contre HCV.

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