A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61K 38/22 (2006.01) A61K 45/00 (2006.01) A61P 1/02 (2006.01) A61P 1/04 (2006.01) A61P 3/10 (2006.01) A61P 7/06 (2006.01) A61P 9/00 (2006.01) A61P 17/00 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 21/00 (2006.01) A61P 21/04 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2528883
[PROBLEMS] To provide a medicinal composition for preventing or treating a Th1 type immunological disease. [MEANS FOR SOLVING PROBLEMS] A medicinal composition to be used in preventing or treating a Th1 type immunological disease containing as the active ingredient a substance capable of differentiating T cells into Th2 type cells by acting on GC-A, which is an NP receptor expressed in dendritic cells, to thereby promote cGMP production and control the cytokine production in the dendritic cells is obtained.
Les problèmes traités par l'invention sont l'obtention d'une composition médicinale de prévention ou de traitement d'une maladie immunologique de type Th1. Le moyen pour résoudre ces problèmes est une composition médicinale à utiliser dans la prévention ou dans le traitement d'une maladie immunologique de type Th1 contenant en tant que principe actif une substance capable de différencier les lymphocytes T en lymphocytes de type Th2 par action sur GC-A, qui est un récepteur NP exprimé dans les cellules dendritiques, pour favoriser ainsi la production de cGMP et réguler la production de cytokine dans les cellules dendritiques.
Asubio Pharma Co. Ltd.
Daiichi Asubio Pharma Co. Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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