A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/22 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 25/28 (2006.01) A61P 31/00 (2006.01) A61P 31/06 (2006.01) A61P 31/20 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)
Patent
CA 2699220
The present invention is directed to the use of the peptide compound Gly-Trp- Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu- Leu-Gly-Pro-D-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2 as a therapeutic agent for the prophylaxis and/or treat-ment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical com-positions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substi-tute containing the peptide Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu- Gly-Pro-D-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D- Trp-Leu-Leu-NH2 optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipi-ent and/or diluent.
La présente invention concerne lutilisation du composé peptidique Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-D-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2 en tant quagent thérapeutique pour la prophylaxie et/ou le traitement du cancer, de maladies auto-immunes, de maladies fibrotiques, de maladies inflammatoires, de maladies neurodégénératives, de maladies infectieuses, de maladies pulmonaires, de maladies cardiaques et vasculaires et de maladies métaboliques. La présente invention concerne en outre des compositions pharmaceutiques de préférence sous la forme dun lyophilisat ou dune solution tampon liquide ou dune formulation de lait maternel artificiel ou dun substitut de lait maternel contenant le peptide Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-D-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2 facultativement conjointement à au moins un véhicule, un cryoprotecteur, un lyoprotecteur, un excipient et/ou un diluant pharmaceutiquement acceptables.
Bacher Gerald
Bevec Dorian
Cavalli Fabio
Cavalli Vera
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Mondobiotech Laboratories Ag
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