C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/06 (2006.01) A61K 31/444 (2006.01) A61K 31/4545 (2006.01) A61K 31/4709 (2006.01) A61K 31/496 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2523426
The present invention provides a compound of Formula I or Formula II: enantiomer, diastereomer, prodrug, solvate, metabolite, or pharmaceutically acceptable salt thereof, wherein constituent variables are provided herein. The compounds of Formula (I) and (II) are modulators of metalloproteases and are useful in treating diseases associated with metalloprotease activity such as arthritis, cancer, cardiovascular disorders, skin disorders, inflammation and allergic conditions.
L'invention concerne un composé représenté par la formule (I) ou (II). L'invention concerne également un énantiomère, diastéréomère, un promédicament, un solvate, un métabolite ou un sel de ceux-ci acceptable sur le plan pharmaceutique, ainsi que des variables constituantes. Les composés représentés par la formule (I) et (II) sont des modulateurs de métalloprotéases et sont utiles dans le traitement de maladies associées à l'activité de la métalloprotéase, notamment l'arthrite, le cancer, les maladies cardiovasculaires, les troubles de la peau, les états inflammatoires et allergiques.
Metcalf Brian
Xu Meizhong
Yao Wenqing
Zhang Fenglei
Zhuo Jincong
Incyte Corporation
Smart & Biggar
LandOfFree
Aza spiro alkane derivatives as inhibitors of metalloproteases does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Aza spiro alkane derivatives as inhibitors of metalloproteases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aza spiro alkane derivatives as inhibitors of metalloproteases will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1690216