C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 333/38 (2006.01) A61K 31/38 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/535 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2601523
Disclosed are compounds for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade. Said compounds are of Formula I I or a solvate, hydrate, pharmaceutically acceptable salt, or prodrug thereof; wherein Ra, Rb, and Rc are defined in the specification, as are A Z, Q, R1 and R2.
La présente invention se rapporte à des composés destinés à traiter les symptômes d'un trouble aigu ou chronique associé à la voie classique de la cascade du complément, ou à un solvate, un hydrate, un sel pharmaceutiquement acceptable ou un promédicament desdits composés. Lesdits composés sont représentés par la formule (II), dans laquelle Ra, Rb, et Rc sont tels que définis dans le descriptif de l'invention, de même que A, Z, Q, R1 et R2.
Ali Farah
Ballentine Shelley
Cummings Maxwell David
Gushue Joan M.
Hufnagel Heather
Janssen Pharmaceutica N.v.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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