A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/55 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 9/52 (2006.01) A61K 31/554 (2006.01)
Patent
CA 2242224
Novel forms of sustained-release microgranules (LP) containing diltiazem are disclosed. The microgranules consist of a neutral granular carrier coated with an active layer including diltiazem or a pharmaceutically acceptable salt thereof as the active principle, a surfactant and a binder, and an outer layer providing sustained release of the active principle (layer LP).
L'invention concerne de nouvelles formes de microgranules à libération prolongée (LP) contenant du diltiazem. Les microgranules sont constitués par un support granulaire neutre, enrobé par une couche active comprenant du diltiazem, ou un sel pharmaceutiquement acceptable de ce dernier en tant que principe actif, un agent tensio-actif et un agent liant, et une couche externe assurant la libération prolongée du principe actif (couche LP).
Debregeas Patrice
Leduc Gerard
Oury Pascal
Suplie Pascal
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Biovail Laboratories International Srl
Laboratoires Des Produits Ethiques Ethypharm
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