Prostate stem cell antigen (psca) variants and subsequences...

Details Prostate stem cell antigen (psca) variants and subsequences... Prostate stem cell antigen (psca) variants and subsequences...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 38/08 (2006.01) A61K 38/17 (2006.01) A61K 38/46 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2526274

PSCA and its encoded protein, and variants thereof, are described wherein PSCA exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, PSCA provides a diagnostic, prognostic, propylactic and/or therapeutic target for cancer. The PSCA gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with PSCA can be used in active or passive immunization.

Cette invention concerne l'antigène PSCA et sa protéine codée, et des variants de ceux-ci. Cet antigène PSCA présente une expression spécifique des tissus dans des tissus adultes normaux et il est exprimé en mode aberrant dans les cancers énumérés dans le tableau I. Par conséquent, l'antigène PSCA fournit une cible diagnostique, pronostique, prophylactique et/ou thérapeutique pour le cancer. Le gène PSCA ou un fragment de celui-ci, ou sa protéine codée ou des variants de ceux-ci, ou un fragment de ceux-ci, peuvent être utilisés pour produire une réponse immunitaire humorale ou cellulaire ; et des anticorps ou des lymphocytes T réagissant à l'anticorps PSCA peuvent être utilisés en immunisation active ou passive.

Affiliated with

Also associated with

Rating

Prostate stem cell antigen (psca) variants and subsequences... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Prostate stem cell antigen (psca) variants and subsequences..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Prostate stem cell antigen (psca) variants and subsequences... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1690963