Recombinant viruses, preparation and use thereof in gene...

Details Recombinant viruses, preparation and use thereof in gene... Recombinant viruses, preparation and use thereof in gene...

C - Chemistry, Metallurgy

12

N

C12N 7/01 (2006.01) A61K 38/46 (2006.01) A61K 48/00 (2006.01) C12N 5/10 (2006.01) C12N 9/20 (2006.01) C12N 15/55 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2190394

Recombinant viruses comprising a heterologous DNA sequence coding for a lipase involved in lipoprotein metabolism. The invention also concerns the preparation and use in therapy of said recombinant viruses, especially for the treatment or prevention of dyslipoproteinemia-related pathologies.

La présente invention concerne des virus recombinants comportant une séquence d'ADN héterologue codant pour une lipase impliquée dans le métabolisme des lipoprotéines, leur préparation, et leur utilisation thérapeutique, notamment pour le traitement et/ou la prévention des pathologies liées aux dysliproprotéinémies.

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