Novel b1 antagonists

Details Novel b1 antagonists Novel b1 antagonists

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/4035 (2006.01) A61K 31/407 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61K 31/472 (2006.01) A61K 31/496 (2006.01) A61K 31/55 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C07D 209/44 (2006.01) C07D 211/08 (2006.01) C07D 211/58 (2006.01) C07D 217/06 (2006.01) C07D 223/16 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 471/10 (2006.01)

Patent

CA 2694251

The present invention relates to compounds of the general formula (I), in which A, Y, R1, R2, R3, R4 and R5 are as defined in claim 1, the enantiomers thereof, the diastereomers thereof, mixtures thereof and salts thereof, especially physiologically tolerated salts thereof with organic or inorganic acids or bases, which have valuable properties, to the preparation thereof, to medicaments comprising the pharmacologically active compounds, the production thereof and the use thereof.

L'invention a pour objet des composés de formule générale (I), dans laquelle A, Y, R1, R2, R3, R4 et R5 sont tels que définis dans la revendication 1, leurs énantiomères, leurs diastéréomères, leurs mélanges et leurs sels, en particulier, leurs sels physiologiquement compatibles avec des acides ou des bases organiques ou inorganiques, lesdits composés présentant des propriétés précieuses. L'invention concerne en outre la production de ces composés, les médicaments renfermant les composés pharmacologiquement efficaces, leur production et leur utilisation.

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