A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 41/00 (2006.01) A61K 31/409 (2006.01) A61K 49/00 (2006.01) A61K 49/04 (2006.01) A61P 35/00 (2006.01) C07D 487/22 (2006.01)
Patent
CA 2440650
The invention relates to medicine and concerns a photosensitizer for detecting and curing tumors. The inventive photosensitizer_is embodied in the form of a composition containing chlorin in the form of salt and alkali metals. The chlorin is composed of 80- 90% of chlorin e6, 2-15% of purpurin 5 and the rest being purpurin 18 - chlorin p6. Said photosensitizer is produced by extracting Spirulina biomass with the aid of acetone. Afterwards said biomass is exposed to acid treatment, neutralization, hydrolysis, extraction of pheophorbide .alpha., dissolution in acetone, addition of a strong base, neutralization and reprecipitation of chlorin e6.
L'invention se rapporte à la médecine et concerne un photosensibilisateur servant à diagnostiquer et traiter les tumeurs. Ce photosensibilisateur se présente sous la forme d'une composition qui contient du chlore sous forme de sel avec un métal alcalin. Le chlore utilisé est constitué de 80-90 % de chlore e>6<, et de 5 à 20 % de purpurine 5, le reste étant de la purpurine 18. On produit le photosensibilisateur par extraction de la biomasse Spirulina à l'aide d'acétone, puis par traitement à l'acide, neutralisation, hydrolyse, extraction de féoforbide alpha , dissolution du féoforbide dans l'acétone, addition de la base forte, neutralisation et réprécipitation du chlore >6.<
Abakumova Olga Yurievna
Gradjushko Alexandr Tikhonovich
Ivanov Andrei Valentinovich
Karmenyan Artashes Vacheevich
Kemov Jury Viktorovich
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Obschestvo S. Ogranichennoi Otvetstvennostiju "rada-Pharma"
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