Spiropiperidine derivatives as melanocortin receptor agonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/10 (2006.01) A61K 31/4725 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 15/00 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 519/00 (2006.01) C07K 5/06 (2006.01)

Patent

CA 2334551

Certain novel spiropiperidine compounds are agonists of melanocortin receptor(s) and are useful for the treatment, control or prevention of diseases and disorders responsive to the activation of melanocortin receptors. The compounds of the present invention are therefore useful for treatment of diseases and disorders such as obesity, diabetes, sexual dysfunction including erectile dysfunction and female sexual dysfunction.

De nouveaux composés de spiropipéridine sont des agonistes des récepteurs de la mélanocortine et sont utiles pour le traitement, la suppression ou la prévention des maladies et des troubles sensibles à l'activation des récepteurs de la mélanocortine. Les composés selon l'invention sont par conséquent utiles pour le traitement des maladies et des troubles tels que l'obésité, le diabète et les dysfonctions sexuelles, y compris la dysérection et les dysfonctions sexuelles féminines.

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